CENE is an initiative to promote brain banking, research, education, and outreach in the field of neurodevelopmental disorders. It is the first large-scale brain bank for neurodevelopmental disorders in Hispano-America. Neurodevelopmental disorders (NDDs) are a set of conditions that present with brain dysfunction due to alterations in the process of brain development. We organize brain banking because human brain tissue is a scarce resource that is obtained from postmortem donations. CENE enables and expands NDD brain research worldwide, particularly with respect to Autism Spectrum Disorder and Fragile X Syndrome, and increases the availability of brain tissue from NDDs to researchers around the globe. These activities are performed in Spanish and English, in Hispano-America and the US.